Therapeutic Antibodies

What are the advantages and disadvantages?

Therapeutic antibody is considered to have the following advantages and disadvantages compared to conventional drugs (low-molecular-weight drugs).

Advantages

1) Higher specificity to target
=> Higher efficacy and less side effects can be expected.

2) Prolonged half life
=> Infrequent dosage

Disadvantages

1) This may increase the economic burden placed on patients
2) Limited route for administration

The above disadvantages may be resolved in the future.

Solution to disadvantage 1)
=>For example, improvements in manufacturing technology may lead to the alleviation of the economic burden of patients.

Solution to disadvantage 2)
=>For example, antibodies with low molecular weight (Fab antibodies, single-chain antibodies, etc.) may be administered in different ways.